Semaglutide is a safe, doctor-prescribed GLP-1 receptor agonist medication that’s prescribed under the brand names Wegovy®, Ozempic®, and Rybelsus® and is part of Zinnia’s anti-aging and medical weight loss program.
It works best when used in combination with a healthy diet and exercise.The largest clinical trial showed that adults taking semaglutide lost an average of almost 15% of their initial body weight — about 12% more than those who didn’t take the medication.
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What is semaglutide?
Semaglutide is an injectable glucagon-like peptide-1 (GLP-1) agonist that’s administered once weekly. It was originally approved in 2017 — at a lower dose under the brand name Ozempic — to help control blood sugar in Type 2 diabetes. People taking Ozempic for blood sugar control also tend to lose weight as an additional benefit. Novo Nordisk studied the medication in people without Type 2 diabetes, but at a higher dose. Now, semaglutide (under the brand name Wegovy) is FDA approved for weight loss. It can be used by adults with a body mass index (BMI) greater than or equal to 30 mg/kg² alone or 27 mg/kg² with at least one weight-related condition (e.g., high blood pressure, high cholesterol, Type 2 diabetes).
Semaglutide should be used in combination with lifestyle changes, including a healthy diet and exercise. Anteneh Roba MD, will monitor progress closely and adjust doses based on your reaction to it.
How does semaglutide work for weight loss?
GLP-1 is an incretin hormone that plays a role in your appetite and digestion. Incretins — hormones released by your digestive tract — are sent out by your body after you’ve eaten a meal. They help lower your blood sugar by triggering insulin release and blocking sugar production. They also slow down how quickly food leaves your stomach (called gastric emptying).
The result of these actions causes you to feel full — lowering your appetite and causing you to lose weight. Medications like GLP-1 agonists are referred to as incretin mimetics since they “mimic” these effects.
